Deffieux Thomas

Deffieux Thomas

Deputy director of Institute Physics for Medicine Paris
Research officer at Inserm
thomas.deffieux@inserm.fr
ORCID profile >
@thomas_deffieux

Education

  • 2008 – PhD in Physics, University Pierre et Marie Curie, Paris, France
    Topics: ultrafast ultrasound imaging, shear wave elastography, shear wave spectroscopy
  • 2005 – Master degree, Université Louis Pasteur, Strasbourg, France
  • 2005 – Engineering degree, Ecole Nationale Supérieure de Physique de Strasbourg, France

Professional experience

  • since 2025 – Deputy director of Institute Physics for Medicine Paris (Inserm U1273, ESPCI Paris-PSL, CNRS UMR 8063)
  • since 2025 – Research director, Inserm, Paris, France
  • 2013-2024 – Research officer, Inserm, Paris, France
  • 2020 – Habilitation à Diriger des Recherches
  • 2010-2012 – Postdoctoral fellow at Institut Langevin, Paris, France
  • 2009-2010 – Postdoctoral fellow at UEIL, Columbia University , New-York, USA

Main awards and distinctions

  • Winner of the BPI ILab Competition for the creation of innovative technology companies in 2015 (project Neuroflow)
  • 2015 Outstanding Paper Award of the IEEE Transactions in Ultrasonics, Ferroelectrics and Frequency Control

Research topics

  • Ultrafast ultrasound imaging and applications
  • functional ultrasound imaging of the brain
  • 3D/4D ultrafast ultrasound imaging
  • ultrasound biomarkers for liver steatosis
  • shear wave elastography imaging

Main publications

1
Rabut C, Ferrier J, Bertolo A, Osmanski B, Mousset X, Pezet S, et al. Pharmaco-fUS: Quantification of pharmacologically-induced dynamic changes in brain perfusion and connectivity by functional ultrasound imaging in awake mice. NeuroImage 2020;222:117231. https://doi.org/10.1016/j.neuroimage.2020.117231.
1
Sauvage J, Porée J, Rabut C, Férin G, Flesch M, Rosinski B, et al. 4D Functional Imaging of the Rat Brain Using a Large Aperture Row-Column Array. IEEE Transactions on Medical Imaging 2020;39:1884–93. https://doi.org/10.1109/TMI.2019.2959833.
1
Bendjador H, Deffieux T, Tanter M. The SVD Beamformer: Physical Principles and Application to Ultrafast Adaptive Ultrasound. IEEE Transactions on Medical Imaging 2020:1–1. https://doi.org/10.1109/TMI.2020.2986830.
1
Rabut C, Correia M, Finel V, Pezet S, Pernot M, Deffieux T, et al. 4D functional ultrasound imaging of whole-brain activity in rodents. Nat Methods 2019:1–4. https://doi.org/10.1038/s41592-019-0572-y.
1
Deffieux T, Demene C, Pernot M, Tanter M. Functional ultrasound neuroimaging: a review of the preclinical and clinical state of the art. Current Opinion in Neurobiology 2018;50:128–35. https://doi.org/10.1016/j.conb.2018.02.001.

Latest publications

1
Zhang G, Vert M, Nouhoum M, Rivera E, Haidour N, Jimenez A, et al. Amplitude-Modulated Singular Value Decomposition for Ultrafast Ultrasound Imaging of Gas Vesicles. IEEE Transactions on Medical Imaging 2025;PP: https://doi.org/10.1109/TMI.2025.3565023.
1
Beliard B, Delay L, Travert-Jouanneau Y, Ialy-Radio N, Isaad C, Réaux-Le Goazigo A, et al. Novel insights into vascular dysfunction in cuprizone-induced demyelination through functional ultrasound imaging. Imaging Neuroscience 2025;3:imag_a_00534. https://doi.org/10.1162/imag_a_00534.
1
Vert M, Zhang G, Bertolo A, Ialy-Radio N, Pezet S, Osmanski B, et al. Transcranial brain-wide functional ultrasound and ultrasound localization microscopy in mice using multi-array probes. Sci Rep 2025;15:12042. https://doi.org/10.1038/s41598-025-96647-7.
1
Vert M, Zhang G, Bertolo A, Ialy-Radio N, Pezet S, Osmanski B, et al. Transcranial brain-wide functional ultrasound and ultrasound localization microscopy in mice using multi-array probes. Scientific Reports 2025;15:1–10. https://doi.org/10.1038/s41598-025-96647-7.
1
Blanquart C, Davenet L, Claisse J, Giroud M, Boulmé A, Jeanne E, et al. Monitoring microvascular changes over time with a repositionable 3D ultrasonic capacitive micromachined row-column sensor. Science Advances 2025;11:eadr6449. https://doi.org/10.1126/sciadv.adr6449.
Nov 21, 2022 | |
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