Deffieux Thomas

Deffieux Thomas

Research officer at Inserm
ORCID profile >


  • 2008 – PhD in Physics, University Pierre et Marie Curie, Paris, France
    Topics: ultrafast ultrasound imaging, shear wave elastography, shear wave spectroscopy
  • 2005 – Master degree, Université Louis Pasteur, Strasbourg, France
  • 2005 – Engineering degree, Ecole Nationale Supérieure de Physique de Strasbourg, France

Professional experience

  • 2020 – Habilitation à Diriger des Recherches
  • since 2013 – Research officer, Inserm, Paris, France
  • 2010-2012 – Postdoctoral fellow at Institut Langevin, Paris, France
  • 2009-2010 – Postdoctoral fellow at UEIL, Columbia University , New-York, USA

Main awards and distinctions

  • Winner of the BPI ILab Competition for the creation of innovative technology companies in 2015 (project Neuroflow)
  • 2015 Outstanding Paper Award of the IEEE Transactions in Ultrasonics, Ferroelectrics and Frequency Control

Research topics

  • Ultrafast ultrasound imaging and applications
  • functional ultrasound imaging of the brain
  • 3D/4D ultrafast ultrasound imaging
  • ultrasound biomarkers for liver steatosis
  • shear wave elastography imaging

Main publications

Rabut C, Ferrier J, Bertolo A, Osmanski B, Mousset X, Pezet S, et al. Pharmaco-fUS: Quantification of pharmacologically-induced dynamic changes in brain perfusion and connectivity by functional ultrasound imaging in awake mice. NeuroImage 2020;222:117231.
Sauvage J, Porée J, Rabut C, Férin G, Flesch M, Rosinski B, et al. 4D Functional Imaging of the Rat Brain Using a Large Aperture Row-Column Array. IEEE Transactions on Medical Imaging 2020;39:1884–93.
Bendjador H, Deffieux T, Tanter M. The SVD Beamformer: Physical Principles and Application to Ultrafast Adaptive Ultrasound. IEEE Transactions on Medical Imaging 2020:1–1.
Rabut C, Correia M, Finel V, Pezet S, Pernot M, Deffieux T, et al. 4D functional ultrasound imaging of whole-brain activity in rodents. Nat Methods 2019:1–4.
Deffieux T, Demene C, Pernot M, Tanter M. Functional ultrasound neuroimaging: a review of the preclinical and clinical state of the art. Current Opinion in Neurobiology 2018;50:128–35.

Latest publications

Binder NF, El Amki M, Glück C, Middleham W, Reuss AM, Bertolo A, et al. Leptomeningeal collaterals regulate reperfusion in ischemic stroke and rescue the brain from futile recanalization: Neuron. Neuron 2024.
Koorliyil H, Sitt J, Rivals I, Liu Y, Bertolo A, Cazzanelli S, et al. Specific and non-uniform brain states during cold perception in mice. J Neurosci 2024:e0909232023.
Griggs WS, Norman SL, Deffieux T, Segura F, Osmanski B-F, Chau G, et al. Decoding motor plans using a closed-loop ultrasonic brain–machine interface. Nat Neurosci 2024;27:196–207.
Caudoux M, Demeulenaere O, Porée J, Sauvage J, Mateo P, Ghaleh B, et al. Curved toroidal row column addressed transducer for 3D ultrafast ultrasound imaging. IEEE Trans Med Imaging 2024:1–1.
Franx BA, Lebrun F, Chin Joe Kie L, Deffieux T, Vivien D, Bonnard T, et al. Dynamics of cerebral blood volume during and after middle cerebral artery occlusion in rats – Comparison between ultrafast ultrasound and dynamic susceptibility contrast-enhanced MRI measurements. J Cereb Blood Flow Metab 2023:0271678X231220698.