Deffieux Thomas

Deffieux Thomas

Research officer at Inserm
thomas.deffieux@inserm.fr
ORCID profile >
@thomas_deffieux

Education

  • 2008 – PhD in Physics, University Pierre et Marie Curie, Paris, France
    Topics: ultrafast ultrasound imaging, shear wave elastography, shear wave spectroscopy
  • 2005 – Master degree, Université Louis Pasteur, Strasbourg, France
  • 2005 – Engineering degree, Ecole Nationale Supérieure de Physique de Strasbourg, France

Professional experience

  • 2020 – Habilitation à Diriger des Recherches
  • since 2013 – Research officer, Inserm, Paris, France
  • 2010-2012 – Postdoctoral fellow at Institut Langevin, Paris, France
  • 2009-2010 – Postdoctoral fellow at UEIL, Columbia University , New-York, USA

Main awards and distinctions

  • Winner of the BPI ILab Competition for the creation of innovative technology companies in 2015 (project Neuroflow)
  • 2015 Outstanding Paper Award of the IEEE Transactions in Ultrasonics, Ferroelectrics and Frequency Control

Research topics

  • Ultrafast ultrasound imaging and applications
  • functional ultrasound imaging of the brain
  • 3D/4D ultrafast ultrasound imaging
  • ultrasound biomarkers for liver steatosis
  • shear wave elastography imaging

Main publications

1
Rabut C, Ferrier J, Bertolo A, Osmanski B, Mousset X, Pezet S, et al. Pharmaco-fUS: Quantification of pharmacologically-induced dynamic changes in brain perfusion and connectivity by functional ultrasound imaging in awake mice. NeuroImage 2020;222:117231. https://doi.org/10.1016/j.neuroimage.2020.117231.
1
Sauvage J, Porée J, Rabut C, Férin G, Flesch M, Rosinski B, et al. 4D Functional Imaging of the Rat Brain Using a Large Aperture Row-Column Array. IEEE Transactions on Medical Imaging 2020;39:1884–93. https://doi.org/10.1109/TMI.2019.2959833.
1
Bendjador H, Deffieux T, Tanter M. The SVD Beamformer: Physical Principles and Application to Ultrafast Adaptive Ultrasound. IEEE Transactions on Medical Imaging 2020:1–1. https://doi.org/10.1109/TMI.2020.2986830.
1
Rabut C, Correia M, Finel V, Pezet S, Pernot M, Deffieux T, et al. 4D functional ultrasound imaging of whole-brain activity in rodents. Nat Methods 2019:1–4. https://doi.org/10.1038/s41592-019-0572-y.
1
Deffieux T, Demene C, Pernot M, Tanter M. Functional ultrasound neuroimaging: a review of the preclinical and clinical state of the art. Current Opinion in Neurobiology 2018;50:128–35. https://doi.org/10.1016/j.conb.2018.02.001.

Latest publications

1
Binder NF, El Amki M, Glück C, Middleham W, Reuss AM, Bertolo A, et al. Leptomeningeal collaterals regulate reperfusion in ischemic stroke and rescue the brain from futile recanalization: Neuron. Neuron 2024. https://doi.org/10.1016/j.neuron.2024.01.031.
1
Koorliyil H, Sitt J, Rivals I, Liu Y, Bertolo A, Cazzanelli S, et al. Specific and non-uniform brain states during cold perception in mice. J Neurosci 2024:e0909232023. https://doi.org/10.1523/JNEUROSCI.0909-23.2023.
1
Griggs WS, Norman SL, Deffieux T, Segura F, Osmanski B-F, Chau G, et al. Decoding motor plans using a closed-loop ultrasonic brain–machine interface. Nat Neurosci 2024;27:196–207. https://doi.org/10.1038/s41593-023-01500-7.
1
Caudoux M, Demeulenaere O, Porée J, Sauvage J, Mateo P, Ghaleh B, et al. Curved toroidal row column addressed transducer for 3D ultrafast ultrasound imaging. IEEE Trans Med Imaging 2024:1–1. https://doi.org/10.1109/TMI.2024.3391689.
1
Franx BA, Lebrun F, Chin Joe Kie L, Deffieux T, Vivien D, Bonnard T, et al. Dynamics of cerebral blood volume during and after middle cerebral artery occlusion in rats – Comparison between ultrafast ultrasound and dynamic susceptibility contrast-enhanced MRI measurements. J Cereb Blood Flow Metab 2023:0271678X231220698. https://doi.org/10.1177/0271678X231220698.
Nov 21, 2022 | |
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