Pernot Mathieu

Pernot Mathieu

Deputy director of Physics for Medicine Paris
Research director at Inserm
mathieu.pernot@espci.fr
ResearcherID: G-3404-2013
ORCID: 0000-0001-6713-4642
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Education

  • 2015 – “Habilitation à Diriger des Recherches”, Université Paris Diderot, France
  • 2004 – PhD in Physics, Université Paris Diderot, France
    “Ultrasound therapy and monitoring: new techniques”
  • 2001 – Master of Science in Acoustics, Université Paris Diderot, France
  • 2001 – Engineering degree at ESPCI (Ecole Supérieure de Physique et Chimie Industrielles), Paris, France

Professional experience

  • since 2019 – Deputy director of Physics for Medicine Paris laboratory, Paris, France
  • since 2016 – Tenured research director, Inserm, Paris, France
  • 2016 – Co-founder of the company Iconeus
  • 2014 – Co-founder of the company Cardiawave
  • 2007-2016 – Tenured research officer, Inserm, Paris, France

Main awards and distinctions

  • 2016 Outstanding Paper Award of the IEEE Transactions in Ultrasonics, Ferroelectrics and Frequency Control
  • 2015 Béatrice Denys Award of the French Foundation for therapeutic innovation
  • Winner of the BPI ILab Competition for the creation of innovative technology companies in 2014 (project Valvopulse) and 2015 (project Neuroflow)
  • Winner of the Concours Mondial de l’Innovation, phase I, II & III (project Valvosoft)
  • ERC Starting Grant 2012 (project ULTRAECHOCARDIO)

Research topics

  • Cardiovascular applications of ultrasound
  • Ultrafast ultrasound imaging of the cardiovascular system
  • 3D ultrafast ultrasound imaging
  • Non-invasive cardiac therapy

Main publications

1
Demeulenaere O, Bertolo A, Pezet S, Ialy-Radio N, Osmanski B, Papadacci C, et al. In vivo whole brain microvascular imaging in mice using transcranial 3D Ultrasound Localization Microscopy. EBioMedicine 2022;79:12. https://doi.org/10.1016/j. ebiom.2022.103995.
1
Demeulenaere O, Sandoval Z, Mateo P, Dizeux A, Villemain O, Gallet R, et al. Coronary Flow Assessment Using 3-Dimensional Ultrafast Ultrasound Localization Microscopy. JACC: Cardiovascular Imaging 2022:16. https://doi.org/10.1016/j.jcmg.2022.02.008.
1
Demené C, Robin J, Dizeux A, Heiles B, Pernot M, Tanter M, et al. Transcranial ultrafast ultrasound localization microscopy of brain vasculature in patients. Nat Biomed Eng 2021;5:219–28. https://doi.org/10.1038/s41551-021-00697-x.
1
Pedreira O, Correia M, Chatelin S, Villemain O, Goudot G, Thiebaut S, et al. Smart ultrasound device for non-invasive real-time myocardial stiffness quantification of the human heart. IEEE Transactions on Biomedical Engineering 2021:1–1. https://doi.org/10.1109/TBME.2021.3087039.
1
Messas E, Rémond MC, Goudot G, Zarka S, Penot R, Mateo P, et al. Feasibility and safety of non-invasive ultrasound therapy (NIUT) on porcine aortic valve. Phys Med Biol 2020. https://doi.org/10.1088/1361-6560/aba6d3.
1
Rabut C, Correia M, Finel V, Pezet S, Pernot M, Deffieux T, et al. 4D functional ultrasound imaging of whole-brain activity in rodents. Nat Methods 2019:1–4. https://doi.org/10.1038/s41592-019-0572-y.
1
Provost J, Garofalakis A, Sourdon J, Bouda D, Berthon B, Viel T, et al. Simultaneous positron emission tomography and ultrafast ultrasound for hybrid molecular, anatomical and functional imaging. NATURE BIOMEDICAL ENGINEERING 2018;2:85–94. https://doi.org/10.1038/s41551-018-0188-z.

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